Notes, primarily of interviews, recorded in 1851 in Missouri. The bulk of the information was obtained in extensive interviews (pages 18-194) in October and November with Daniel Boone's son Nathan and the latter's wife, Olive Van Bibber Boone. Although their discussion centered about the life, adventures, and personality of Daniel Boone, there is also biographical material on Simon Kenton and Lewis Wetzel; genealogical data on the Boone, Bryan, Callaway, and Van Bibber families; and numerous references to Nathan Boone's own career, particularly his military service in the War of 1812 in Missouri and the upper Mississippi Valley.

A very few other papers - letters to Draper, copies of articles, and newspaper clippings - are found preceding and following the interview notes. At the beginning of the notebook Draper prepared a detailed name index with chronological entries under each name.