Seven pocket memoranda books bound together, containing interview notes taken in the fall of 1845 mainly in western Virginia (West Virginia) and Ohio in the vicinity of Wheeling.

Topics discussed include the sieges of Wheeling; Samuel Brady; William Crawford; David Shepherd; Lewis Wetzel and other members of the Wetzel family; Ebenezer, Jonathan, and Silas Zane; and numerous other pioneers in this region. Among persons interviewed was an elderly black survivor of the Wheeling sieges, Rachael Johnson, whom Draper visited again the following year. (The 1846 interview notes are in 3 S.) A few pages at the end of the volume contain notes by Draper from the archives of Bourbon County, Kentucky, and from scattered issues of the Pennsylvania Packet, 1773-1774. Each memorandum book contains an individual index by Draper.