Papers, 1791-1794, dealing chiefly with Indian troubles and measures for defense before and after St. Clair's defeat in 1791. David Shepherd's principal correspondents, 1791-1793, were Benjamin Biggs, Richard Butler, Henry Knox (ten letters), James Marshel, Anthony Wayne, and Virginia governors Beverley Randolph and Henry Lee. Two letters in 1791, one written by Henry Bedinger, the other by George Washington concern conflicting land claims at Round Bottom. Among Sheperd's occasional correspondents were his brother Abraham and David Bruce, John Connell,. John Love, William McMechen (McMahon), John Neville, Zachariah Sprigg, Andrew Swearingen, Alexander White, Robert Woods, and Ebenezer Zane. Drafts of ten letters by David Shepherd to Knox, Wayne, and others are interspersed among the incoming correspondence. Although military plans and events constitute the major topics, a few scattered allusions to other matters occur in the 1791 letters: e.g., Alexander White's comments on excise taxes and Abraham Shepherd's remarks on agriculture, weather, and smallpox inoculation.

Ohio County military records include a payroll (1791); lists of men serving as spies (1792-1793); rolls, most of which are undated, for companies captained by Edmund Baxter, Lewis Bonnett, Francis McGuire, and William McMechen; receipts, accounts, and certificates for rations, for medical care, and for service as scouts and spies; discharge papers for several militiamen; two undated petitions from county residents, one pertaining to spy service, the other to a ferry across the Ohio River. Closing the volume is a partially illegible, undated plat of lands owned by the Shepherds and others.