The collection consists of records generated or accumulated during the educational and political careers of Guilford M. Wiley. Materials include correspondence (1931-1933; 1945-1954), scattered issues of the La Crosse Central High Tribune (1922; 1928), miscellaneous materials (circa 1938-1954), materials from the National Council of Presbyterian Men (1943-1954), and loose newspaper clippings grouped by topic (1939-1954).
Many of the newspaper clippings pertain to information about the La Crosse School District, although other topics are covered as well. Other materials include items from Wiley's political career (1949-1954), and twenty photographic postcards depicting the evangelist Reverend Billy Sunday (1908). An indexed newspaper clipping scrapbook (1938-1939) containing articles pertaining to the La Crosse public schools is also included.
