Within a year of the founding of De Pere, Wisconsin, in 1836, a Sabbath School was organized by George and William White. In 1849 the services were transferred to the Brown County Courthouse, and on December 1 the church was formally organized under the auspices of the Presbyterian Board of Domestic Missions. The first pastor was the Reverend John Stewart, who died of exposure shortly after assuming his position. The first church structure was built in 1854 with lumber donated by Godfrey Miller. A fire, which swept a large segment of the community, destroyed the church in 1884. While the congregation met in the Jackson & Sons Building, a new church was built and dedicated on October 18, 1887. The Reverend Howard A. Talbot, D.D., began a long pastorate in 1889. He retired in 1910 but was called out of retirement in 1918 and served until 1929. Membership continued to climb to nearly 700 in the 1960s. In 1956 a new site was purchased and work was begun on new church buildings. The new sanctuary was dedicated on December 8, 1963, and a new organ was installed in 1971.
