Abstract: Records of the U. S. Weather Bureau’s La Crosse (Wis.) office that include administration (1872-1947), meteorological data (1872-1948; 1951-1974), and Mississippi River data (1874-1969). Administrative records include correspondence (1872-1912) and a register of events (1905-1947) which logs non-meteorological events that occurred at the weather station. Meteorological records (1872-1974) include daily, weekly, monthly and yearly reports from the La Crosse station, as well as yearly federal reports of the chief of the Weather Bureau. Mississippi River materials include daily river stages across the country (1890-1969) and records of observations of the Mississippi River at La Crosse (1874-1905).